Charlie Sheen as Himself
Naturally, Charlie Sheen played himself in the episode “The Griffin Equivalency”. He is a loved household name across the globe, the 54-year-old actor has many appearances under his belt like the film 9/11.
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Regina King as Janine Davis
Regina King acts as the director of employee relations at Caltech. Her recurring role as the hard yet hilarious director is one for the books. Additionally, King has acted as Brenda Jenkins on the series 227, The Boondocks, Jerry Maguire and Southland.